Take your dinner game to the next level with this Spinach Artichoke Stuffed Chicken recipe! Cream cheese, Mozzarella, artichoke hearts, and spinach are mixed together, stuffed into a butterflied chicken breast, and then pan-seared and baked in the oven. They’re easy enough for a quick weeknight dinner, or fancy enough to serve for a holiday party!

Low carb spinach artichoke chicken is served as a healthy, keto dinner.
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One of my all-time FAVORITE appetizers is creamy Spinach Artichoke Dip.

If it is at a party, you know where to find me – hovering around that bowl the entire night.

During one of my recent cravings, I decided to switch up this popular dip by turning it into a main dish… spinach and artichoke stuffed chicken breasts!

After a bit of experimentation, the results are in… they are a hit!! My family can’t get enough of them!

Why This Dish is a Winner

Artichoke hearts and spinach combine with two types of cheese to make a filling that is creamy, cheesy, flavorful, and out-of-this-world delicious.

They’re so simple to make, ready in under 30 minutes and they only have 2 grams of carbs per serving! So all of you low-carb and keto dieters can rejoice, because this recipe has your name on it.

If you need a few more easy, but impressive dinner recipe ideas, then check out this Olive Garden Chicken Marsala, Chicken Cordon Bleu, and this Glazed Balsamic Chicken!

Ingredients

For the exact measurements and detailed instructions, you can jump to the recipe.

Chicken breasts, spinach, artichokes, cream cheese, mozzarella, garlic, and yogurt are the ingredients used in this recipe.
  • Chicken. You’ll need boneless skinless breasts that are at least 1-inch thick in order to stuff them with ease. Boneless thighs may be substituted if they are thick enough.
  • Spinach. Previously frozen and thawed out spinach is the best type to use.  Fresh spinach can be substituted, but you will need to saute it for a few minutes in order to cook it down.
  • Artichoke. Canned artichoke hearts that have been rinsed and drained are then cut into small pieces. You can use fresh artichoke hearts, but it does take a lot more work.
  • Cheeses. A combination of cream cheese and shredded Mozzarella cheese make up the bulk of this filling. Feel free to substitute the Mozzarella with Gruyere, Asiago, Parmesan cheese, or even white cheddar.
  • Seasonings. You’ll need dried oregano along with salt and black pepper throughout the preparation process along with fresh parsley.
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How to Make Spinach Artichoke Stuffed Chicken

Jump to the recipe for the full instructions, ingredient amounts, and a printable recipe.

  • Prepare the chicken. Place the breasts on a cutting board. You want a sharp, serrated knife when butterflying the meat. Cut evenly through the middle of the breast from the THIN side of the breast. Avoiding your fingers, cut about halfway in using a sawing motion. Do NOT cut all the way through! When you are about halfway through, try to cut in a way that makes a pocket in the thickest part of the chicken that will hold the filling rather than cut straight over to the other side.
  • Make the spinach filling. Wrap the thawed spinach in a cheesecloth or paper towels and wring out any excess moisture. Combine the drained spinach with the softened cream cheese, Mozzarella cheese, artichoke hearts, minced garlic, oregano, salt, and pepper in a medium-sized mixing bowl. Use a spoon or a spatula to thoroughly mix the ingredients.
  • Stuff chicken with filling. Scoop up about 1-2 tablespoons of the spinach mixture at a time.  Place the creamy filling all of the way in the back of the breast, and repeat this process until it is totally full. Each breast should fit about ⅓ to ½-cup of filling. If you are concerned about the filling falling out while searing or baking, you can hold the chicken together with a toothpick, if desired. Sprinkle the remaining salt and pepper on each side of the breast.
  • Sear and bake. Add the olive oil to a large pan, a cast iron skillet works great. After it’s sizzling over medium or medium-high heat, place the breasts in the pan in a single layer.  Sear chicken for 4 to 5 minutes per side. You should start to see a golden brown crust. Then, place the skillet in the preheated oven. Bake in a 350℉ oven for 22 to 24 minutes. The chicken is done when an instant-read thermometer reaches 165℉.
  • Serve the spinach artichoke chicken immediately with some fresh chopped parsley.
Stuffed chicken breast is plated for an easy, low-carb dinner.

FAQs

What is stuffed chicken made of?

Stuffed chicken is a versatile dish that can be made with a variety of fillings. In this recipe, a twist on spinach artichoke dip is stuffed inside the prepared chicken breast. However, you can choose other flavors, just be sure there is some kind of cheese to hold the filling together.

What’s the best way to stuff chicken breast?

The best way to stuff chicken breasts is to halfway butterfly them, creating a pocket in the middle as you cut. This method ensures most of the filling stays inside the chicken during cooking.

Can I use fresh spinach instead of frozen?

While you can use fresh  baby spinach, you will want to cook it first until it’s wilted to remove any extra liquid. Otherwise, your stuffed chicken will be runny and the filling will fall apart.

What’s the best way to drain frozen spinach?

The best way to drain frozen spinach is to completely thaw it and then wring it out in a cheesecloth or paper towels.

What do I do if I have leftover filling?

Most likely you will end up with a little extra filling after stuffing the chicken breasts.  During the last 3-5 minutes of cooking or baking, simply add the remaining dip to the skillet or baking dish to warm it up. Serve the filling on top of the chicken for anyone who wants a bit more!

Recipe Tips

  • Create a hole. Be sure to stop cutting halfway through the breast and make a pocket for the filling in the middle.
  • Soft is key. Let the cream cheese come to room temperature before mixing it into the filling.
  • Wring it out. Squeeze all of the moisture out of the spinach so the filling doesn’t fall apart.
  • Season well. Sprinkle salt and pepper on the outside of the chicken breasts before baking.
  • Fresh is key. Mince fresh garlic cloves for the most flavor.
Chicken stuffed with a homemade spinach artichoke filling is served on a plate for dinner.

What to Serve with Stuffed Chicken?

Much like any other chicken recipe, these stuffed chicken breasts taste incredible when served with many types of vegetables.

For starters, try Mashed CauliflowerSautéed Zucchini and SquashGreen Beans Almondine, Green Beans with Vinegar, and Roasted Cauliflower if you’re looking for low-carb options.

You can’t go wrong with starchier vegetables like these Baked Sweet Potato FriesSmashed Potatoes, or Southern Corn Fritters.

More Chicken Breast Recipes

Try another delicious chicken breast recipe, like any of these, that the whole family will love.

Baked BBQ Chicken Breasts, Sheet Pan Chicken and Asparagus, and Hot Honey Chicken are so full of flavor.

Caprese Chicken and Balsamic Grilled Chicken will impress anyone who comes over for dinner parties.

Don’t miss out on Baked Honey Mustard Chicken, Creamy Pesto Chicken Gnocchi, or Honey Balsamic Glazed Chicken.

Fiesta Lime Chicken will make you feel like you got takeout!

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5 from 5 votes

Spinach Artichoke Stuffed Chicken Recipe

Take your dinner game to the next level with this Spinach Artichoke Stuffed Chicken recipe! Cream cheese, Mozzarella, artichoke hearts, and spinach are mixed together, stuffed into a butterflied chicken breast, and then pan-seared and baked in the oven. 
Chicken stuffed with a homemade spinach artichoke filling is served on a plate for dinner.
Yield 5 servings
Prep 15 minutes
Cook 15 minutes
Total 30 minutes
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Ingredients 

  • 5 medium-sized chicken breasts about 1 ¼ to 1 ½ pounds.
  • 6 ounces frozen spinach thawed
  • 4 ounces cream cheese room temperature, softened*
  • ½ cup Mozzarella cheese finely shredded
  • ½ cup artichoke hearts drained, finely chopped
  • 2 cloves garlic finely minced
  • ½ teaspoon oregano dried
  • 1 ¼ teaspoons salt divided
  • ½ teaspoon black pepper divided
  • 2 tablespoons oil olive or avocado
  • Fresh parsley finely chopped, optional

Instructions 

  • Preheat the oven to 350 degrees.
  • Butterfly the Chicken Breasts: Add chicken breasts to a cutting board. Place your non-dominant hand on the top of one (making sure your fingers are out of the way!) and then insert a sharp knife into the thinner side of the meat. Carefully cut the breast in half using a sawing motion, stopping before you cut all of the way through. Once you get about halfway, begin to create more of a pocket which will help hold some of the filling in.
    5 medium-sized chicken breasts
  • Make the Spinach Filling: Using either a cheese cloth or paper towels, drain the thawed spinach to remove any excess liquid. Add the drained spinach, softened cream cheese, Mozzarella cheese, artichoke hearts, minced garlic, oregano, ¾ teaspoon salt, and ¼ teaspoon pepper to a medium-sized bowl. Mix with a spoon or spatula until well combined.
    6 ounces frozen spinach, 4 ounces cream cheese, ½ cup Mozzarella cheese, ½ cup artichoke hearts, 2 cloves garlic, ½ teaspoon oregano, 1 ¼ teaspoons salt, ½ teaspoon black pepper
  • Stuff Chicken with Filling: Carefully fill each chicken breast with equal amounts of the spinach artichoke filling. (About ⅓ to ½-cup will fit into each one.) Then sprinkle the remaining ½ teaspoon salt and ¼ teaspoon black pepper over all sides of the breasts.
    1 ¼ teaspoons salt, ½ teaspoon black pepper
  • Sear and Bake: Add oil to a large oven-proof skillet over medium heat. Once it’s sizzling, add chicken breasts in a single layer. Cook for 4-5 minutes on one side, or until seared, and then flip the chicken over. Add skillet to the preheated oven and continue cooking for 22-24 minutes, or until the chicken reaches an internal temperature of 165 degrees.
    2 tablespoons oil
  • Serve chicken with a sprinkle of finely chopped parsley, if desired. Enjoy!
    Fresh parsley
Last step! If you make this, please leave a review letting us know how it was!

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5 from 5 votes

Video

Notes

  • Cream cheese: You can also microwave cream cheese in the bowl for 30 seconds if removed directly from the refrigerator.
  • Chicken: Don’t slice all of the way through the chicken.
  • Prep-Ahead: You can butterfly the chicken and make the filling the day before. If needed, you can completely prepare the chicken up until baking and keep in the fridge for up to one day.
  • Storage: Store leftover chicken in an airtight container in the refrigerator for up to 3-4 days. 
  • Freezing: This chicken can also be frozen for up to 3-4 months.
  • Reheating: For the best results, warm this chicken back up in the oven. You can use the microwave, as well.

        Nutrition

        Calories: 331kcal, Carbohydrates: 5g, Protein: 30g, Fat: 21g, Saturated Fat: 7g, Polyunsaturated Fat: 3g, Monounsaturated Fat: 7g, Trans Fat: 0.04g, Cholesterol: 104mg, Sodium: 852mg, Potassium: 593mg, Fiber: 2g, Sugar: 1g, Vitamin A: 4615IU, Vitamin C: 8mg, Calcium: 145mg, Iron: 2mg

        Nutrition information is automatically calculated, so should only be used as an approximation.

        Made this recipe?Leave a comment below!
        London Brazil taking a bite from a bowl of food.

        Hi, I'm London!

        Come join me as we turn everyday dinners into Weeknight Winners with simple and downright delicious recipes, made mostly from scratch, that will make everyone at the table smile!

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        Comments

        1. Made this dish I fast seared chicken breast than baked it at 375 for a half hour. I also sprinkled with garlic powder it was delicious

          1. What a great idea to add a bit of garlic powder! And that’s good to know that it can be baked in the oven, too! Thanks for the comment!

        2. What type of Greek Yogurt do you use? Most I come across (in Canada) contain sugar. Any brands you can personally recommend?

          1. Hi Jess!! Wow – Canada! My husband and I are hoping to visit there soon! As for the Greek yogurt, I tend to buy the Chobani plain Greek yogurt (4 grams of sugar with no added sugar.) If you are unable to find this one, here is a wonderful resource you can check out that shows you their sugar/nutritional values. Thanks so much for asking! Can’t wait to hear what you think of the recipe 🙂

            1. I will be trying ALL of your Keto recipes 😁 ..they all look delicious and I’m sure they will be. Thanks for sharing London you’re an amazing cook. You may not realize this, but you are doing more than sharing delicious recipes here, you’re making it easy ( and delicious) for me to provide healthy meals for my family and friends. You’re making lives happier and healthier so kudos to you lady.

              1. Hi Krystle!! And wow!! Your comment just made my day. That is exactly what I am trying to do with Evolving Table – make lives happier and healthier and help you provide healthy meals for your loved ones. I have just never had someone say it quite like that so THANK YOU! You have encouraged me more than you know!

        3. 4 stars
          If you use fresh artichoke, it won’t soften in the middle of the chicken, leave it all in the pan to soften.

        4. 5 stars
          I made this last night. It was amazing! My husband went on and on about it! The only thing I did differently was adding a little minced garlic to the mixture. That’s just because we really like garlic. 🙂 Thank you for this recipe!

          1. I’m totally on board with the more garlic the better 😉 So happy you and your hubby enjoyed it, Stephanie! Thanks so much for your comment and rating!

            1. Hi I would like to make it this recipe today but the only thing I have in the fridge right now is muenster cheese would that be okay?

              1. Hi! I have not personally tried it with muenster, but always encourage experimentation! My only warning is that it might not work quite as well as the combo in the recipe. Would love to hear how it turns out for you!

        5. I have never made spinach artichoke dip before, (I know), for the artichokes are they fresh or canned what do you use? This looks delicious. My family needs to cut down on the carbs, this looks like a great meal to start with.

          1. Hi Cindy! Great question. The aritchokes are the heart you buy in the cans. No need to dissect an entire artichoke for this recipe 😉 Thanks for your question!